华中科技大学化学与化工学院 华中科技大学化学与化工学院

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师资队伍

  • 姓  名: 郑炎松   zhengyansong

  • 出生年月:1961-10

  • 学历: 博士

  • 职称: 教授

  • 专业方向:有机合成

  • 电    话:

  • Email:zyansong@hotmail.com

  • 个人主页:

教育与研究经历


1982年华中师范大学化学系学士

1996年中国科学院化学研究所博士

1998年浙江大学高分子科学与工程学系博士后

1999.12–2001.4香港大学化学系博士后

2002.2–2004.8美国密西西比大学药物化学系访问学者

1998–现在,华中科技大学化学与化工学院工作

研究领域与兴趣


1. AIE大环化合物的合成及分子识别和自助装性能研究

    最近发现一类新型的具有聚集诱导发光(Aggregation-Induced Emission,AIE) 特性的有机分子,在溶液中没有荧光,在聚集状态下能产生强烈的荧光,由于这类分子在固体光电材料以及化学与生物传感器等方面具有重大的应用价值引起了极大的重视和广泛的关注,2015年被Thomson Reuters评为在化学与材料科学领域第二大顶级研究前沿。将AIE分子连接成大环后,由于环状化合物比开链化合物刚性更强,按照AIE分子内运动受限(RIM)机理,环状化合物将具有更强的荧光发射强度;环状化合物本身具有洞穴,通过洞穴大小和形状对客体分子的限制,可以显著提高AIEgen分子作为传感器的选择性。对一系列环状AIEgen分子的研究表明,它们在AIE现象增强、分析检测中灵敏度和选择性提高、客体分子调节荧光发射、超分子催化、AIE机理揭示和证明、四苯乙烯螺旋手性应用、分子储存、分离和释放等方面比开链AIEgen分子具有更大优势。例如我们发现AIE大环折叠体形成的发光纳米粒子,用十多种硝基芳香烃做淬灭实验时,其荧光更容易被爆炸物TNT淬灭,可用于检测每毫升空气中飞克级TNT,相当于探测犬的灵敏度,是目前荧光分析方法中灵敏度最高的。

2. 具有AIE特性的有机分子合成及手性识别性能研究

我们首次提出将分子的手性与AIE特性联系起来,进行手性识别。通过合成手性AIE酸或手性AIE碱,与手性的客体碱或客体酸进行对映选择性的聚集,就象手性拆分一样,使客体碱或酸的一个对映体聚集产生强烈荧光,而另一个对映体不聚集或者具有不同聚集形式而导致无荧光或者弱荧光,甚至产生波长相差很大的荧光,达到手性识别和对映体组成定量分析的目的。发现将AIE特性用于手性识别和对映体组成定量分析上具有特别高的选择性,特别广泛的适用性和特别高的灵敏度。

3. 有应用价值的重要有机化合物,药物中间体的合成以及一些药物分子合成方法及路线的改进。

教学情况


承担了有机化学,有机化学实验,高等有机化学,精细有机化学品化学,有机合成,不对称合成等课程的教学。

承担项目与课题


承担了国家自然科学基金、自主创新基金、以及企业的一些技术服务等项目。

代表性成果


· Hai-Tao Feng, Ying-Xue Yuan, Jia-Bin Xiong, Yan-Song Zheng,* Ben Zhong Tang,* Macrocycles and cages based on tetraphenylethylene with aggregation-induced emission effect, Chem Soc. Rev. 2018, DOI: 10.1039/c8cs00444g.

· Zhen Wang, Hui Ma, Tian-Long Zhai, Guang Cheng, Qin Xu, Jun-Ming Liu,* Jiakuan Yang, Qing-Mei Zhang, Qing-Pu Zhang, Yan-Song Zheng,* Bien Tan,* Chun Zhang,* Networked cages for enhanced CO2 capture and sensing, Adv. Sci. 2018, 5, 1800141.

· Wei-Guo Qiao, Jia-Bin Xiong, Ying-Xue Yuan, Hong-Chao Zhang, Dong Yang, Minghua Liu, Yan-Song Zheng,* Chiroptical property of TPE triangular macrocycle crown ethers from propeller-like chirality induced by chiral acids, J. Mater. Chem. C 2018, 6, 3427-3434.

· Jia-Bin Xiong, Jin-Hua Wang, Bao Li,* Chun Zhang,* Bien Tan,* Yan-Song Zheng,* Porous interdigitation molecular cage from tetraphenylethylene trimeric macrocycles that showed highly selective adsorption of CO2 and TNT vapor in air, Org. Lett 2018, 20, 321324.

· Jia-Bin Xiong, Hai-Tao Feng, Jin-Hua Wang, Chun Zhang,* Bao Li,* Yan-Song Zheng,* Tetraphenylethylene foldamers with double hairpin-turn linkers, TNT-binding mode and detection of highly diluted TNT vapor, Chem. Eur. J. 2018, 24, 2004–2012.

· Jia-Bin Xiong, Ying-Xue Yuan, Lian Wang, Jian-Ping Sun, Wei-Guo Qiao, Hong-Chao Zhang, Miao Duan, Hongwei Han, Song Zhang,* Yan-Song Zheng,* Evidence for aggregation-induced emission from free rotation restriction of double bond at excited state, Org. Lett. 2018, 20, 373376.

· Wen-Zhao Xie, Hong-Chao Zhang, Yan-Song Zheng,* Tetraphenylethylene tetracylhydrazine macrocycle with capability for discrimination of n-propanol from i-propanol and highly sensitive/selective detection of nitrobenzene, J. Mater. Chem. C 2017, 5, 10462–10468.

· Hai-Tao Feng, Jia-Bin Xiong, Jun Luo, Wen-Fang Feng, De-Suo Yang, Yan-Song Zheng,* Selective host–guest co-crystallization of pyridine-functionalized tetraphenylethylenes with phthalic acids and multicolor emission of the co-crystals, Chem. Eur. J. 2017, 23, 644–651.

· Jia-Bin Xiong, Hai-Tao Feng, Jian-Ping Sun, Wen-Zhao Xie, Dong Yang, Hua-Ming Liu, Yan-Song Zheng,* The fixed propeller-like conformation of tetraphenylethylene that reveals aggregation-induced emission effect, chiral recognition, and enhanced chiroptical property, J. Am. Chem. Soc. 2016, 138, 1146911472.

· Jia-Bin Xiong, Wen-Zhao Xie, Jian-Ping Sun, Jin-Hua Wang, Zhi-Hua Zhu, Hai-Tao Feng, Dong Guo, Hui Zhang, Yan-Song Zheng,* Enantioselective recognition for many different kinds of chiral guests by one chiral receptor based on tetraphenylethylene cyclohexylbisurea, J. Org. Chem. 2016, 81, 37203726.

· Hai-Tao Feng, Jia-Bin Xiong, Yan-Song Zheng,* Biao Pan, Chun Zhang, Lei Wang, Yongshu Xie, Multicolor emissions by the synergism of intra/intermolecular slipped π−π stackings of tetraphenylethylene-diBODIPY conjugate, Chem. Mater. 2015, 27, 78127819.

· Chun Zhang,* Zhen Wang, Liangxiao Tan, Tian-Long Thai, Shen Wang,* Bien Tan,* Yan-Song Zheng,* Xiang-Liang Yang, Hui-Bi Xu, A porous tricyclooxacalixarene cage based on tetraphenylethylene, Angew. Chem. Int. Ed. 2015, 54, 9244–9248.

· Hai-Tao Feng, Xin Zhang, Yan-Song Zheng,* Fluorescence turn-on enantioselective recognition of both chiral acidic compounds and α-amino acids by a chiral tetraphenylethylene macrocycle amine, J. Org. Chem. 2015, 80, 8096−8101.

· Jin-Hua Wang, Jia-Bing Xiong, Yan-Song Zheng,* Tetraphenylethylene imidazolium macrocycle: synthesis and selective fluorescence turn-on sensing of pyrophosphate anions, RSC Adv. 2015, 5, 60096–60100.

· Jin-Hua Wang, Hai-Tao Feng, Yan-Song Zheng,* Synthesis of Tetraphenylethylene Pillar[6]arenes and the Selective Fast Quenching of Their AIE Fluorescence by TNT, Chem. Commun. 2014, 50 (77), 11407–11410.

· Jin-Hua Wang, Hai-Tao Feng, Jun Luo, Yan-Song Zheng,* Monomer Emission and Aggregate Emission of an Imidazolium Macrocycle Based on Bridged Tetraphenylethylene and Their Quenching by C60, J. Org. Chem. 2014, 79 (12), 5746–5751.

· Song-Song, Jin-Hua Wang, Hai-Tao Feng, Zhi-Hua Zhu, Yan-Song Zheng,* Supramolecular 1 hydrogel based on amphiphilic calix[4]arene and its application in the synthesis of silica nanotubes, ASC Adv. 2014, 4(47), 24909–24913.

· Jin-Hua Wang, Yi-Chang Chen, Yan-Song Zheng,* Chang-Hong Shen, Selective Nitration of Calix[4]arenes that Easily Gave Inherently Chiral Calix[4]arenes, J. Incl. Phenom. Macro. Chem. 2014, DOI 10.1007/s10847-014-0413-7.

· Chun Zhang,* Yan-Song Zheng,* et al., Tetraphenylethylene-based expanded oxacalixarene: synthesis, structure, and its supramolecular grid assemblies directed by guests in the solid state, J. Org. Chem. 2014, 79(6), 2729–2732.

· Song-Song, Hua-Fei Zheng, Dong-Mi Li, Jin-Hua Wang, Hia-Tao Feng, Zhi-Hua Zhu, Yi-Chang Chen, Yan-Song Zheng,* Monomer Emission and Aggregate Emission of TPE Derivatives in the Presence of γ-Cyclodextrin, Org. Lett. 2014, 16 (8), 2170–2173.

· Hai-Tao Feng, Song-Song, Yi-Chang Chen, Chang-Hong Shen, Yan-Song Zheng,* Self-assembled tetraphenylethylene macrocycle nanofibrous materials for the visual detection of copper(II) in water, J. Mater. Chem. C 2014, 2, 2353–2359

· Hai-Tao Feng, Yan-Song Zheng,* Highly Sensitive and Selective Detection of Nitrophenolic Explosives by Using Nanospheres of a Tetraphenylethylene Macrocycle Displaying Aggregation-Induced Emission, Chem. Eur. J. 2014, 20, 195 – 201.


获奖与荣誉


郑炎松,罗钧,莫婉玲,杯芳烃衍生物的合成、手性识别及催化聚合反应的研究,湖北省自然科学奖三等奖,2010年。